Everton is Sam Allardyce's seventh different managerial job in the Premier League
Charsley, 21, lines out at full-back for the Toffees in Cyprus - in what will be the club's final game in Europe this season.
Everton plan on taking fringe players and a number of youngsters to take on Apollon as Allardyce looks to rest as many of his senior stars as possible ahead of Sunday's Merseyside derby against bitter city rivals Liverpool.
Sam Allardyce's side prop up Group E and are exiting the competition no matter what happens this evening.
Shakespeare will take the reins of Everton's first-team against Apollon Limassol on Thursday in the absence of Sam Allardyce, who is unable to attend the match.
17-year-old Ireland-eligible defender Michael Collins and keeper Mateusz Hewelt, who played schoolboy football with Stella Maris and Shelbourne, are substitutes tonight.
James McCarthy and Sandro Ramirez are two players that would have expected to play some part against a team that now occupy fifth place in the Cypriot First Division, with suggestions that the former was hoping to get 60 minutes under his belt. You are always learning about your players and forming opinions about them.
"I just think they're so explosive, so fast, so good going forward".
Both players were left out of the win over Huddersfield on Saturday and are keen to get an opportunity to show the new manager what they are capable of doing.
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