Former Liverpool player, Raheem Sterling - presently City's top scorer in the league this season - can expect a hostile reaction from the home crowd again. One of the hardest to clear will be this trip to Anfield.
With that being the case, Fred is one of their best players, if not the best and is now a target for Manchester City who have made their move. The little Brazilian was as brilliant as ever - even when effectively playing under duress.
The Blues have returned winless in last three matches in all competitions.
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Graeme Le Saux gives his views on life after Coutinho and whether Man City can continue their unbeaten streak at Anfield on Sunday.
Sane, who was snapped up by City boss Pep Guardiola in the summer of 2016, admitted: "Before I joined City, I was talking with them". When you also factor in City's return of almost three goals a game, it's quite easy to assume the Reds will be the underdog on Sunday.
The higher the level you play at, the more intuitive your decisions need to be and there have been a few games when he's been caught out. That said with Jurgen Klopp's gegenpressing Liverpool are the team best suited to fighting back against Manchester City's onslaught. "We will see on Sunday".
Most experts scratched their heads at the time, but City proved everyone wrong with a vengeance. Going to any of the top four away from home is hard. For those of us that enjoy watching top quality players, it's a shame we won't see him in the Premier League and I can understand why Liverpool supporters are downbeat, but sometimes you just have to be realistic.
Liverpool begin life after Philippe Coutinho with the toughest test in European football as they host runaway Premier League leaders Manchester City at Anfield today.
City's 5-0 win over Liverpool in September was the first time they had scored five or more goals in a game against the Reds since March 1937. Klopp's men have also better balanced the overall demands of the fixture list, winning three and drawing one.
The Citizens have had the lead at half time and full time in five out of their last six league games. The runaway league leaders haven't lost in England all season, while Liverpool haven't lost a match anywhere for almost three months.
Richard Cooke's report reads: "Manchester City manager Pep Guardiola is refusing to describe his team as champions in waiting". The Dons are the only club to do this since the Second World War.
Defeat at Anfield would still leave City as heavy favourites to collect a third Premier League title in seven seasons, but Guardiola had not started crunching numbers.
Beauvillier, Barzal lead Isles to 7-2 rout of Rangers
He then got his 15th of the season when he finished his own rebound on another Islanders odd-man rush at 4:11, making it 4-1. The boos were raining down on the Blueshirts as Lundqvist was summoned, and the mood wasn't much different on the bench.
Mizzou falls on the road to Arkansas
After three games with 20 turnovers during nonconference play, the Tigers have averaged just 10 turnovers through three SEC games. Daniel Gafford and Dustin Thomas bent over in frustration as the basketball rolled out of bounds under the Missouri basket.
Zach LaVine scores 14 in return to Bulls' lineup
Chicago, which made its first six 3-pointers, finished 17 of 36 from the arc, tying the most made against the Pistons this season. LaVine made his first shot, a 27-footer from the right of the key, before he assisted Robin Lopez's basket inside.
South Africa wins toss, bats in 2nd test against India
India was in position for a rare victory in South Africa in the opening test in Johannesburg in December 2013. What is the "most consistent" player for? But once that was done with, he was at his stroke-playing best.