techkenyot.com
techkenyot.com July 23, 2018


Immunotherapy shows lung cancer promise

17 April 2018, 11:27 | Silvia Roy

Immunotherapy shows lung cancer promise

Immunotherapy shows lung cancer promise

One study, conducted by scientists at New York University, involved more than 600 patients with advanced lung cancer.

Patients in the study had advanced non-small cell lung cancer, the most common type. It's called immunotherapy. Doctors have been using Keytruda and Opdivo for several years treating lung cancer.

The findings, published in the the New England Journal of Medicine, were reported on Monday at the American Association for Cancer Research annual meeting in Chicago. If you want to see long-term survival, you've got to give immunotherapy as soon as possible. "We have patients on these immunotherapies are alive more than eight years".

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Notably, the incidence rate of lung cancer among non-smoking Chinese females is rising comparatively faster compared with those in western countries. The data are not conclusive, but Herbst said, "In lung cancer, my suspicion is these drugs are the same, like Coke vs. Pepsi".

Immunotherapy, which harnesses the body's immune system to attack tumors, is known to improve survival in patients who have already been treated with chemo. By killing some tumor cells, chemotherapy could pop open the bags, release the contents and help immune cells — unleashed by the checkpoint drugs — to identify their prey.

The study, a phase III clinical trial testing treatment effectiveness and side effects, included 616 patients at 118 medical facilities around the globe.

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For non-squamous non-small cell lung cancer patients, median survival with chemotherapy alone is somewhere around 11 or 12 months, he said.

Using the immunotherapy resulted in "significantly longer overall survival and progression-free survival than chemotherapy alone", the study found. Median survival is met when 50% of the patients die.

The estimated survival after a year was 69 per cent in those taking the immunotherapy drugs compared to 49 per cent who only had chemotherapy.

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