techkenyot.com
techkenyot.com March 23, 2019


HPV test should replace Pap test for cervical cancer screening, study suggests

05 July 2018, 10:04 | Silvia Roy

A new study found that the HPV test was better than the Pap smear in detecting precancerous changes that can lead to cervical cancer

A new study found that the HPV test was better than the Pap smear in detecting precancerous changes that can lead to cervical cancer

In the U.S., using both the Pap smear and the HPV test, or co-testing, is the gold standard recommended by the U.S. Preventative Services Task Force. Testing for cancer-related human papillomavirus (HPV), which causes 99.7 percent of cervical cancer, outperformed the effectiveness of Pap smears in women over the age of 30.

According to American College of Obstetricians and Gynecologists (ACOG) women aged 21 to 29 years should have a Pap test every three years while women aged between 30 to 65 years should have a Pap test along with a HPV test every five years or a Pap test every three years.

Suboptimal specificity of the HPV test is still a limiting factor for widespread adoption of the test as a cancer screening tool, write the authors of the editorial, "especially among populations of young women who often carry HPV infections that regress without oncogenic outcome".

Numerous medical groups have said that before moving to HPV testing only, they needed to see clinical trial results - such as the kind provided by the new head-to-head study - to determine which test, over time, was better at detecting the precancerous changes. At the end of the four years the women were tested using both tests.

"Most cases of cervical cancer happen in women who have not been regularly screened, or who have been screened, but don't have access to appropriate treatment", she says.

Greenpeace crashes Superman-shaped drone into French…
According to company management, we are talking about two drones, one of which was intercepted by the gendarmerie. Last week 19 activists were handed suspended prison sentences for breaking into another plant in November 2017.

In an accompanying editorial, L. Stewart Massad, MD, of the Washington University School of Medicine in St. Louis, argued that cytology testing does not significantly improve the accuracy of HPV testing, but it does increase costs and false-positive results. According to the article, the researchers surveyed 5080 women treated for early-stage breast cancer by 377 surgeons in Georgia and Los Angeles between 2013 and 2015.

Pap smears involve scraping cells from the cervix and examining them for cancerous changes, also known as "cytology" testing. The vaccine is given to teens and young adults, but generations of women are still at risk of cervical cancer because HPV eventually infects most people at some point.

The National Cancer Institute's Mark Schiffman, who has done extensive research on HPV, said the study confirmed that it's important to move from the Pap smear to the HPV test alone.

Women who had a negative HPV test at the start of the study were much less likely to develop CIN3+ within 48 months than women who had a negative smear test at the start of the study.

In most provinces, Pap tests are recommended every three years. In both the groups, the final co-testing discovered more abnormal cells within some of the women who initially tested negative.

'Is football coming home? May quizzed after England win against Colombia
The two Colombian footballers who missed penalties to hand England victory in their World Cup tie have received death threats. Their manager Gareth Southgate embraced his support staff, aware that the hoodoo had finally been undone.

After four years, the women who got HPV tests were less likely to have serious changes that can lead to cervical cancer, a diagnosis of cervical intraepithelial neoplasia 2 or 3 (CIN2 and CIN3), Ogilvie's team found. According to the same trial study group, the test finds 94.6 percent of suspected cervical cancer cases. The two groups were again tested with both the methods post of 4 years.

"This is one study", he said.

That kind of early detection is the hallmark of cervical cancer prevention, because health-care providers can take action to treat precancerous cells before they become cancer.

In addition to finding more precancers in the initial screening, women who had the HPV test had a "significantly lower likelihood" of having precancer in the cervix when they exited the study four years later. "The ASCCP [American Society for Colposcopy and Cervical Pathology] pointed out that just doing the HPV testing would miss some people, and so they advocated for co-testing". Instead of a physician scraping the cells from the back of a woman's cervix before visually inspecting them for signs of abnormality, an HPV test analyzes cells found in vaginal and cervical secretions.

Its replacement? The human papillomavirus test. "The real benefit of co-testing is with the HPV test", she said.

Brazil will find it hard to topple Belgium
That was some encounter, but trying to beat Brazil will be the greatest test the Red Devils have faced in Russian Federation to date .

Medical students learn how to insert a speculum, part of the process of performing a Pap smear.



Other News

Trending Now

Willian unfazed by Barcelona rumours
Fellow Brazilians Philippe Coutinho and Paulinho already ply their trade at the La Liga champions and Willian admits the trio get on well.

Modi government approves Rs 200 hike in MSP for paddy
Paddy is the main kharif (summer sown) crop, the sowing of which has already begun with the onset of southwest monsoon. The MSP is like a shock absorber by the government to safeguard farmers against any sudden fall in produce prices.

Georgia quarterback Fromm breaks bone in non-throwing hand
One source added to Mansell that Fromm may have to wear a soft cast for a period of time. Georgia fans were panicking a little bit earlier this afternoon.

Coinbase launches its custodial service, claims SEC’s cooperation
In order to achieve the status of an SEC-regulated broker-dealer, Coinbase Custody has partnered with Electronic Transaction Clearing (ETC).

NASA's Dawn Probe Sends Photos of Dwarf Planet Ceres to Earth
The photographs revealed odd bright spots on the surface, which drew immediate attention from the scientific community. This image of Ceres' limb was obtained by NASA's Dawn spacecraft on May 30 , 2018 from an altitude of about 280 miles.

Iran diplomat arrested over bomb plot against US-backed opposition
It's not clear whether he was referring to people granted green cards or naturalized when 'granted citizenship'. This story was was also broadcast on Fox News and metioned in a tweet by President Donald Trump earlier today.

United States congressmen meet Russian officials in St. Petersburg
The senator leads a delegation of United States lawmakers, who arrived in Moscow after a short stay in St. The congressmen also met their counterparts in both houses of the Russian parliament.

Texas mother arrested for allegedly selling young children
Investigators are still looking into the woman and said there could be additional charges filed against her as well. The DPS investigation revealed that Garza was also attempting to sell two little girls.

Thai cave rescuers in race against time
The chance of rainfall increases from Sunday, and alongside the increased rainfall is the threat of heavier downpours. But water continues to flow in, no matter how many holes have been blocked, water still continues to pour in".

Sacha Baron Cohen Video Teases Trump-Centric Project
In the run up to the 2016 election, Cohen shot a sequence for The Brothers Grimsby involving then candidate Trump contracting HIV. The footage is actually of Trump attacking the comedian and " Borat " creator. "Learn about being amusing ".