techkenyot.com
techkenyot.com October 17, 2018


HPV test should replace Pap test for cervical cancer screening, study suggests

05 July 2018, 10:04 | Silvia Roy

Enlarge this image

Enlarge this image

In the U.S., using both the Pap smear and the HPV test, or co-testing, is the gold standard recommended by the U.S. Preventative Services Task Force. Testing for cancer-related human papillomavirus (HPV), which causes 99.7 percent of cervical cancer, outperformed the effectiveness of Pap smears in women over the age of 30.

According to American College of Obstetricians and Gynecologists (ACOG) women aged 21 to 29 years should have a Pap test every three years while women aged between 30 to 65 years should have a Pap test along with a HPV test every five years or a Pap test every three years.

Suboptimal specificity of the HPV test is still a limiting factor for widespread adoption of the test as a cancer screening tool, write the authors of the editorial, "especially among populations of young women who often carry HPV infections that regress without oncogenic outcome".

Numerous medical groups have said that before moving to HPV testing only, they needed to see clinical trial results - such as the kind provided by the new head-to-head study - to determine which test, over time, was better at detecting the precancerous changes. At the end of the four years the women were tested using both tests.

"Most cases of cervical cancer happen in women who have not been regularly screened, or who have been screened, but don't have access to appropriate treatment", she says.

Willian unfazed by Barcelona rumours
Fellow Brazilians Philippe Coutinho and Paulinho already ply their trade at the La Liga champions and Willian admits the trio get on well.

In an accompanying editorial, L. Stewart Massad, MD, of the Washington University School of Medicine in St. Louis, argued that cytology testing does not significantly improve the accuracy of HPV testing, but it does increase costs and false-positive results. According to the article, the researchers surveyed 5080 women treated for early-stage breast cancer by 377 surgeons in Georgia and Los Angeles between 2013 and 2015.

Pap smears involve scraping cells from the cervix and examining them for cancerous changes, also known as "cytology" testing. The vaccine is given to teens and young adults, but generations of women are still at risk of cervical cancer because HPV eventually infects most people at some point.

The National Cancer Institute's Mark Schiffman, who has done extensive research on HPV, said the study confirmed that it's important to move from the Pap smear to the HPV test alone.

Women who had a negative HPV test at the start of the study were much less likely to develop CIN3+ within 48 months than women who had a negative smear test at the start of the study.

In most provinces, Pap tests are recommended every three years. In both the groups, the final co-testing discovered more abnormal cells within some of the women who initially tested negative.

Steph & Ayesha Curry Welcome Third Child
On Wednesday, both Steph and Ayesha revealed the news on their IG pages, with Steph revealing their son's name, Canon W. Stephen wrote, "On this journey, on this quest. protect me".

After four years, the women who got HPV tests were less likely to have serious changes that can lead to cervical cancer, a diagnosis of cervical intraepithelial neoplasia 2 or 3 (CIN2 and CIN3), Ogilvie's team found. According to the same trial study group, the test finds 94.6 percent of suspected cervical cancer cases. The two groups were again tested with both the methods post of 4 years.

"This is one study", he said.

That kind of early detection is the hallmark of cervical cancer prevention, because health-care providers can take action to treat precancerous cells before they become cancer.

In addition to finding more precancers in the initial screening, women who had the HPV test had a "significantly lower likelihood" of having precancer in the cervix when they exited the study four years later. "The ASCCP [American Society for Colposcopy and Cervical Pathology] pointed out that just doing the HPV testing would miss some people, and so they advocated for co-testing". Instead of a physician scraping the cells from the back of a woman's cervix before visually inspecting them for signs of abnormality, an HPV test analyzes cells found in vaginal and cervical secretions.

Its replacement? The human papillomavirus test. "The real benefit of co-testing is with the HPV test", she said.

Russian couple divorce over Ronaldo-Messi debate
He is very unpredictable", Meunier told Globo Esporte . "It was a very hard match, we knew the quality of our opponents". We know we have quality and collectiveness to beat them, but we also know that it will not be easy".

Medical students learn how to insert a speculum, part of the process of performing a Pap smear.



Other News

Trending Now

Thousands protests across USA against Trump’s immigration policies
More than 500 women, including a member of Congress, were arrested on Thursday in the US Capitol complex protesting Trump's immigration policy.

Zimbabwe's national rugby team sleeps on Tunisian streets after ill-treatment
The Sables- Zimbabwe rugby side and their managers had traveled to the North African country ahead of their World Cup Qualifier match on Saturday.

AAP Government's First Order After Top Court Victory Rejected: 10 Points
The elected government of Delhi will be able to decide on postings and transfers of officers, he added in a tweet. The Bench noted that the Union has executive power over land, police and public order.

Trump moves to block China Mobile's USA entry, citing security concerns
American lawmakers have, for example, described the phone-makers Huawei and ZTE (ztcoy) as " a severe national security threat ". The NTIA claimed state-owned China Mobile is subject to exploitation, influence, and control by the Chinese government .

Planet’s birth captured on camera for the first time
For decades, astronomers have thought that planets form out of the rotating disks of debris that encircle most newly formed stars. Analysis of this spectrum indicated that its atmosphere is cloudy.

Coffee drinking connected to lower risk of death, study finds
Those who drank around 6 to 7 cups of coffee per day had around a 16 percent lower risk of death , the study found. Moreover, to get the benefit, it didn't matter whether someone metabolized caffeine slowly or quickly.

Blac Chyna Reportedly Been Dating 19-Year Old Devin Haney For Months
The couple then hit the headlines again amid claims Blac was pregnant with the 18-year-old's child, but these later appeared to be unfounded.

Greenpeace crashes Superman-shaped drone into French…
According to company management, we are talking about two drones, one of which was intercepted by the gendarmerie. Last week 19 activists were handed suspended prison sentences for breaking into another plant in November 2017.

Oil Surges Above $75 in NY as Supply Outages Outpace OPEC
But Tehran has threatened to take drastic action on the oil supply in retaliation against Trump's attempt to curb its exports. USA crude futures CLc1 were up 19 cents at $74.33 a barrel, within sight of Tuesday's 3-1/2-year high above $75 a barrel.

Trump Reportedly Pressed Officials About Invading Venezuela
President Trump announced the possibility of a military option for the Venezuelan crisis without first consulting his Cabinet. The only of the leaders named by the AP was Colombian President Juan Manuel Santos .