Anderson's fifth set alone lasted almost 3 hours as his semifinal became a test of endurance more than skill.
Anderson agreed, adding: 'I really hope we can address this'. "You're never really safe", Roger Federer said of Anderson after his five-set loss Wednesday to the former Illini.
Anderson had already won the first point of the game but was blown back while returning yet another of Isner's monstrous serves.
Kveta Peschke, 43, and her American partner Nicole Melichar advanced with a 6-3, 4-6, 7-5 victory over Gabriela Dabrowski and Yifan Xu. Not only is he advancing to the first Grand Slam semifinal of his career at Wimbledon, he and his wife, Highland Park native Madison McKinley, are expecting their first baby girl.
Isner also broke the record for most aces at Wimbledon, hitting 214 at the tournament and 53 on Friday.
It was that kind of ingeniousness that was needed to break the serve-hold-serve-hold deadlock that went on for nearly three hours in the deciding set alone as Anderson became the first South African man in 97 years to reach the Wimbledon final.
The game dragged on for a total of six hours and 36 minutes, with the final set alone taking two hours and 54 minutes.
That point ended up actually setting up the winning break for Anderson.
Many would argue Anderson and Isner deserve similar recognition after the great mates warmly embraced at the net before receiving a standing ovation from tennis's most famous centre-court crowd.
The decisive moment came in game 49 of the decider, when Anderson lifted himself off the floor, kept the point alive with a left-handed shot and went on to complete just the sixth break of the match.
Isner had nothing left to give after his 70-68 record-setter eight years ago, and lost his next match.
Greensboro native John Isner was eliminated in the Wimbledon semifinals Friday.
The 31-year-old is eyeing a 13th major after making the semi-finals of a Slam for the first time since finishing runner-up at the 2016 US Open. Anderson served for the third at 5-3, got broken, and then had a pair of set points in that tiebreaker, double-faulting one away. "I say that because our rivalry, what have you, goes back way before the pro tour".
"I feel pretty awful", Isner said afterward.
Johnson & Johnson told to pay $4.7bn in powder case
The jury reached a unanimous verdict yesterday to award compensatory damages for 22 plaintiffs that averaged US$25 million apiece. Johnson & Johnson has been sued by more than 9,000 women who claim its talcum powder contributed to their ovarian cancer.